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- Risk-Free Trial: Enjoy EVY worry-free for 90 days. If you’re not fully satisfied, we offer a no-hassle, full refund.
- 95% of Users: Experience positive results in as short as 5 weeks.
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I tried a competitor first because it was less expensive and wasn’t able to tolerate the harsh flickering. The masking technology of the EVY makes all the difference, allowing me and my wife to use it frequently and realize the intended benefits.
– Steve T.
The Choice is Clear—Invest in a Future of Clarity and Vitality
Cognitive decline can take away the most precious parts of life, but it doesn’t have to.
Unlike 40Hz gimmicks and alternatives, EVY is backed by published research, neuroscience engineering, rigorous development, and testing.
Knee replacement surgery is $30,000. What is a healthy brain worth? $60,000? More?
There’s no greater value than $1999 or 4 payments of $499 to support your brain for years to come.
It’s far less than what one would expect to pay for a precision-engineered device with patented technology. The current lower pricing is intentional. We aim to put EVY in as many hands as possible to gather real-life user experiences and spread awareness of the benefits.
Order today at the current low pricing to support mental sharpness, memories, independence, and connections to loved ones.
Mai Nguyen
PhD, UC Berkley
CEO, Optoceutics
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Founded on Academic and Clinical Research
OptoCeutics is founded on academic and clinical research. Below, you can find a collection of academic research papers that we, together with top-tier academic research institutions such as the Danish Technical University, the University of California Berkeley, Roskilde University Hospital, and Copenhagen University, have contributed to the international research field.
We are exceedingly proud of our work with internationally recognized research institutions.
Filter our research by topics that interest you.
Research Square et. al. 2024
This study tested gamma frequencies (36-44 Hz) for visual stimulation in Alzheimer's treatment. Results showed increased EEG power at all frequencies but no specific preference. Individual responses varied, suggesting a need for personalized treatment.
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Agger et. al. 2023
This article is about a study that investigated the safety and effectiveness of using flickering light to treat Alzheimer's disease. The study found that the treatment was safe and well-tolerated, and there were some indications that it may have had a positive effect on cognitive function in some patients.
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Agger et. al. 2022
Researchers are investigating a novel treatment option for Alzheimer's disease using a Light Therapy System (LTS) that targets neural networks through non-invasive light temporally modulated at 40 Hz using Invisible Spectral Flicker (ISF). Early indications from small-scale studies on mice and humans suggest potential benefit in reducing the load of amyloid-β and tau and increasing visuo-spatial memory while seemingly being safe and feasible for use.
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Carstensen et. al. 2020
This article discusses a potential treatment option for Alzheimer's disease involving exposure to 40 Hz stroboscopic light therapy, which has shown promise in slowing the progression of the disease in mice but can cause discomfort in patients. The article presents a new technique called Invisible Spectral Flicker (ISF), which can entrain the same oscillations in various areas of the brain without causing discomfort.
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Carstensen et. al. 2021
This article discusses the use of LED lights with specific temporal modulations (in the range of 24-48 Hz) for potential therapeutic treatments of Alzheimer's disease. The article highlights the importance of understanding the Critical Flicker-Fusion Frequency (CFF) and presents a potential method for determining CFF using a portable experimental setup.
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Agger et. al. 2022
This article explores the potential use of a specific type of visual stimulus, 40 Hz invisible spectral flicker (ISF), for inducing gamma entrainment in the brain. The study found that ISF was able to induce 40 Hz neural activity entrainment, similar to 40 Hz stroboscopic light, but with less discomfort and better potential for use in future clinical trials.
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Zibrandtsen et. al. 2020
This A study examined how age affects the brain's response to intermittent photic stimulation (IPS) at 40 Hz, which has potential benefits for Alzheimer's disease. The induced gamma oscillations were mainly concentrated in the occipital area of the brain. These findings are important for future research on the therapeutic potential of photic stimulation for Alzheimer's patients.
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Zibrandtsen et. al. 2020
This A study examined how age affects the brain's response to intermittent photic stimulation (IPS) at 40 Hz, which has potential benefits for Alzheimer's disease. The induced gamma oscillations were mainly concentrated in the occipital area of the brain. These findings are important for future research on the therapeutic potential of photic stimulation for Alzheimer's patients.
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Liu et. al. 2022
This article discusses a study that used 40-Hz high-frequency repetitive transcranial magnetic stimulation (rTMS) to modulate gamma-band oscillations in patients with Alzheimer's disease (AD). The results showed that this technique improved cognitive function and prevented gray matter volume loss in the brain.
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Martorell et. al. 2019
This article reports that inducing gamma oscillations in the brain using auditory tone stimulation (gamma entrainment using sensory stimulus or GENUS) improves spatial and recognition memory, and reduces amyloid in the auditory cortex and hippocampus of Alzheimer's disease mouse models. The study also found that combining auditory and visual GENUS produced wide-ranging effects throughout the brain, reducing amyloid plaques and improving cognitive function.
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Adaikkan et. al. 2019
This article is about how inducing gamma oscillations with visual stimulation can reduce amyloid plaques and phosphorylated tau in mouse models of neurodegeneration. The study shows that the stimulation can preserve neuronal and synaptic density in multiple brain areas and improve cognitive performance.
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Iccarino et. al. 2016
This article is about how fast brain waves called gamma oscillations may help reduce the buildup of plaque in the brain associated with Alzheimer's disease. The researchers used light flickering at a specific frequency to stimulate these brain waves and observed a reduction in plaque levels in mice, suggesting a potential non-invasive treatment for Alzheimer's disease in the future.
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Christov et. al. 2016
This article investigates how the brain changes as people age, specifically looking at how the brain's electrical activity changes during tasks involving auditory discrimination. The study found that as people get older, their brain activity in certain frequency bands changes, which could have implications for understanding how cognitive processes change with age.
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Murty et. al. 2021
This article is about how gamma rhythms in the brain may be used as a potential screening tool for mild cognitive impairment (MCI) and AD in humans. The study found that stimulus-induced gamma rhythms were significantly lower in MCI/AD subjects compared to their age- and gender-matched controls, suggesting that this could be a useful diagnostic tool.
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Murty et. al. 2020
This article discusses the findings of a study on the effect of normal aging on gamma oscillations in elderly subjects. The study found that power and center frequency of gamma rhythms decreased with age, and this reduction was more pronounced in fast gamma compared to slow gamma, which could be important for developing biomarkers of cognitive decline in the elderly.
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Guntekin et. al. 2022
This article discusses how Alzheimer's disease affects the gamma oscillations in the resting-state EEG of patients. The study found that the gamma dominant peak frequency of AD patients was lower compared to healthy elderly and young subjects, and this could be related to AD progression.
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Reider et. al. 2010
This article is about how human gamma-band activity (GBA) is associated with various cognitive functions such as perception, attention, memory, and consciousness, and how it can predict behavioral measures such as reaction times and correct response rates. The review also suggests that studying GBA can help understand the mechanisms underlying neuropsychiatric disorders.
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Gray et. al. 1988
This article discusses how neurons in the visual cortex of cats respond to specific visual stimuli, and how their firing patterns are synchronized with local field potential oscillations. The results suggest that this synchronous oscillation is specific to the cortical neurons, and may provide a way for different regions of the cortex to coordinate their activity.
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Herrmann et. al. 2001
This article discusses how the brain perceives visual objects and how their features are bound together. The study explores the role of neural oscillators in processing visual stimuli at different frequencies and their potential resonance frequencies, which could be a basis for gamma oscillations in binding experiments.
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Norcia et. al. 2015
This article is about a technique called steady-state visual evoked potentials, which is used to study how the brain processes visual information. The technique involves presenting visual stimuli that change at a regular frequency and measuring the resulting electrical activity in the brain. The article describes how the technique has been used in various scientific and applied settings and provides examples of research findings in vision science.
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Scientific Advisors
Dr. Jeffrey Cummings
Prof., MD, ScD, Neurology
A world-renowned Alzheimer’s researcher and clinical trial leader.
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Dr. Henrik Zetterberg
Prof., MD, Neurochemist
Biomarkers expert on Alzheimer’s disease & other brain disorders.
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Dr. William Jagust
Prof., MD. Alzheimer’s Expert
Distinguished expertise in PET imaging & Alzheimer’s research.
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Dr. Silke Kern
Prof., PhD, MD,
Extensive experience in operational management of clinical trials.
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Dr. Jan Pedersen
Biophysicist, PhD, MSc,
Innovative & highly experienced leader in drug discovery research.
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Prof. Lance Kriegsfeld
Author, Vice Chair & Professor
Expert in animal research & preclinical study design.
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VISION & DIRECTION
Executive Leadership
Dr. Ngoc Mai Nguyen
CEO & Co-Founder
Visionary Leader in Neurotech & Therapeutic Innovation
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Dr. Marcus Carstensen
CSO & Co-Founder
Innovator in Optical Science & Neurodegenerative Therapies
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OPERATIONAL SUPPORT
Board Of Directors
Ngoc Mai Nguyen, PhD
Marcus S. Carstensen, PhD
David Hardwick
Vivienne Ming, PhD
Kaare Agerholm Danielsen, PhD
Jes Broeng, PhD
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FAQ
General
Usage
What is 40 Hz Light Stimulation?
40 Hz light stimulation is a therapeutic approach that involves exposing individuals to light flickering at a frequency of 40 hertz (Hz), where the light blinks on and off 40 times per second. The key aspects of 40 Hz light stimulation include:
Gamma Rhythms Restoration: The therapy stimulates gamma wave rhythms, which are important for cognitive functions and often disrupted in Alzheimer’s patients, as well as those suffering from dementia and generalized cognitive decline.
Reduction in Alzheimer’s Pathology: An added potential benefit is studies have shown that 40 Hz stimulation may also reduce the levels of amyloid and tau proteins in the brain, which are hallmarks of Alzheimer’s pathology.
Improvement in Cognitive Functions: Studies indicate that 40 Hz therapy may also improve cognition and preserve synapses in Alzheimer’s patients.
Non-Invasive Nature: As a non-invasive therapy, EVY LIGHT® delivers sensory stimulation through light and sound (if desired), offering a safer alternative to more invasive treatments. 40 Hz sound therapy is available on the app at no extra cost. You will need your own headphones.
What conditions does EVY LIGHT® help with?
Users of EVY LIGHT® report improvements in sleep, mood, energy, focus, and memory while living with conditions like Alzheimer’s, dementia, and cognitive impairment.
Is Masked 40 Hz Light dangerous?
EVY LIGHT® is CE marked and FCC marked, meaning that we have verified compliance with the essential safety requirements as indicated in the applicable United States and European Directive and Regulation bodies.
Masked 40 Hz Light is non-invasive, however, if you suffer from photosensitivity or are susceptible to epileptic seizures, you might negatively react to the stroboscopic effect of the light. Therefore, we encourage anyone who might be at risk to first contact their doctor before using EVY LIGHT®.
How do I use EVY LIGHT®?
EVY LIGHT® is simple to use.
➤ Turn on the light and have it well within your field of view for 1 hour a day or it can also be used, for example, for 15 minutes four times a day or 30 minutes two times a day.
➤ The light is most effective when used for a minimum of 60 minutes a day (preferably in the first half of the day, and at least 4 hours before going to bed).
Why do you recommend to use EVY LIGHT® in the first half of the day?
Exposure to bright light at the wrong times alters the body’s internal clock, or circadian rhythm, and can make your brain stay “awake” later than you intend.
A good sleep-and-wake cycle is extremely important for many functions in our everyday life. We recommend that you use EVY LIGHT® through the first half of the day, if possible.
What can I do while using EVY LIGHT®?
We’re pleased to tell you there are many activities you may perform while using your EVY LIGHT®!
Either sitting or standing, whatever is comfortable to you.
A few examples include:
- board games
- eating snacks or meals
- engaging in conversations in person or virtually
- reading, writing, working at the computer
- listening to audiobooks, music, or podcasts
- using the phone
- watching TV
- working
Can I talk on the phone while using EVY LIGHT®?
Yes. You can use any type of phone while using EVY LIGHT®.
The device capabilities will not disrupt your phone technology or use.
Contact Details
- info@optoceutics.com
- US +1 (415) 881 - 1433
- EU +45 50 20 60 71
- 2120 University Ave.
Berkeley, California 94720
New: Independent Memory Care Study
EVY is a general wellness product and is not intended to diagnose, treat, prevent, or cure any disease or medical condition.
